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Tutorial 5 Image Registration

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This tutorial is under development. Please use the provided online materials to learn more.

Autoalign: Methodology and Technology for the Alignment of Functional Magnetic Resonance Imaging Time Series: Image Registration: The Case of Functional MRI

by: Carlo Ciulla

Functional Magnetic Resonance Imaging (FMRI) is currently acquired in Time Series to detect non-invasively, in-vivo functional activity of the human brain, thus determining four dimensional data sets. Although detectable, due to the short time in between the acquisition of the brain volumes, head motion is usually minimal; however its correction is quite relevant to the consistency of the analysis of the FMRI data. This book presents methodology and technology for registering FMRI Time Series. Math formulations are given along with software engineering descriptions of the algorithms employed for the specific task of FMRI alignment. The book also presents the code that implements the methodology, which was written combining ANSI C, Open GL and Matlab. The intended audience of this work is composed by undergraduate and graduate students in academic disciplines within the domain of computer science applications, applied signal processing and computational engineering. This book is of interest to anyone in the interests of how computer science, mathematics and engineering may combine together to forge the developmental effort in the quest for the solution of a technical challenge.

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Klein et al, 2009


Article title | Evaluation of 14 nonlinear deformation algorithms applied to human brain MRI registration.

Uylings et al, 2005


Article title | Consequences of large interindividual variability for human brain atlases: converging macroscopical imaging and microscopical neuroanatomy. (requires subscription or contact author for reprint).

Lacadie et al, 2008


Article title | More accurate Talairach coordinates for neuroimaging using non-linear registration.

CBU Imaging Wiki

Title | The MNI brain and the Talairach atlas.
This page discusses the MNI brain, and the difference between the MNI brain and the brain in the Talairach atlas.

Advanced Normalization Tools

The ANTS package is designed to enable researchers with advanced tools for brain and image mapping. Many of the ANTS registration tools are diffeomorphic*, but deformation (elastic and BSpline) transformations are available.

Brett et al, 2002


Title | The problem of functional localization in the human brain (requires subscription or contact author for reprint).